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Canagliflozin-d4

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SL-10226

Canagliflozin-d4, >98%

CAS No. : [1997338-61-0]

Synonyms : JNJ-28431754-d4

IUPAC Name : (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl-2,3,5,6-d4)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

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Chemical Properites
Mol. Formula :
C24H21D4FO5S
Mol. Weight :
448.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Canagliflozin-d4 is a deuterium labelled version of Canagliflozin. This can be used as an analytical labelled reference standard. Canagliflozin is a selective SGLT2 inhibitor is being developed for the treatment of type 2 diabetes.

References : Liang Y. et al.: PLoS One 7(2), e30555, 2012; Kobuchi S. et al.: Biomed Chromatogr., 30(10), 1549-1555, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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