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Capecitabine EP impurity E

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Capecitabine EP impurity E, >98%

CAS No. : [162204-30-0]

Synonyms : 5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine

IUPAC Name : Isopentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate

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Chemical Properites
Mol. Formula :
C15H22FN3O6
Mol. Weight :
359.35
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Capecitabine, which is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase. Capecitabine is a chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.

References : PharmD C. M. et al.: Clinical Therapeutics, 27(1), 23-44, 2005; Guichard S. M. et al.: Eur J. Cancer, 44(2), 310-317, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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