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Capeserod hydrochloride

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SI-6743

Capeserod hydrochloride, >98% (HPLC)

CAS No. : [191023-43-5]

Synonyms : SL-65.0155

IUPAC Name : 5-(8-Amino-7-chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-3-(1-phenethylpiperidin-4-yl)-1,3,4-oxadiazol-2(3H)-one hydrochloride

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C23H25ClN4O4 • HCl
Mol. Weight :
493.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Capeserod hydrochloride selectively targets 5‑HT4(e) receptors with sub‑nanomolar affinity (Ki= 0.6 nM) and functions as a partial agonist at 5‑HT4(b/e) splice variants, increasing cAMP production (IC50= 244 nM and 29 nM). Its pronounced cognitive‑enhancing effects support its use in models of memory impairment and dementia‑related pathology.

References : Moser P. C. et al.: Journal of Pharmacology and Experimental Therapeutics, 302(2), 731-741, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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