Capmatinib dihydrochloride hydrate

SI-8037

Capmatinib dihydrochloride hydrate, >98% (HPLC)

CAS No. : [1865733-40-9]

Synonyms : INCB-28060 dihydrochloride hydrate; INC-280 dihydrochloride hydrate

IUPAC Name : 2-Fluoro-N-methyl-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzamide dihydrochloride hydrate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Capmatinib dihydrochloride hydrate is a potent ATP‑competitive c‑MET inhibitor (IC₅₀= 0.13 nM) that blocks c‑MET signaling, suppresses proliferation and migration, induces apoptosis, and is metabolized by CYP3A4 and aldehyde oxidase.

References : Liu X. et al.: Clin. Cancer Res., 17(22), 7127-38, 2011; Baltschukat S. et al.: Clin. Cancer Res., 25(10), 3164-3175, 2019; Capmatinib S. D. Drugs, 80(11), 1125-1131, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.