Captopril-d3

SI-5778

Captopril-d₃, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1356383-38-4]

MDL No. : MFCD18385047

Synonyms : SQ 14225-d₃

IUPAC Name : (S)-1-((S)-3-Mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic-2,5,5-d₃ acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Captopril-d₃ is a deuterium labelled version an analog of Captopril. An antihypertensive agent, which is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC₅₀ of 7.9 μM.

References : Afrin S. et al.: J. Agric Food Chem., 64(11), 2263-2268, 2016; Esmaeili S. et al.: Chem Biol Interact., 265, 24-35, 2017; Li N. et al.: Bioorg Med Chem Lett., 24(1), 386-389, 2014; Tzakos A. G. et al.: Bioorg Med Chem Lett, 16(19), 5084-7,2006; Song J. C. et al.: Clin Pharmacokinet., 41(3), 207-24,2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.