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Captopril EP impurity J

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SI-5788

Captopril EP impurity J, >98% (HPLC)

CAS No. : [64838-55-7]

MDL No. : MFCD00792449

IUPAC Name : ((S)-3-(Acetylthio)-2-methylpropanoyl)-L-proline

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G55.00
Back Order  Estimated to ship on 04 October 2026
5G225.00
Back Order  Estimated to ship on 04 October 2026
10G425.00
Back Order  Estimated to ship on 04 October 2026
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Note: SI-5788 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C11H17NO4S
Mol. Weight :
259.32
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Captopril (Captopril EP impurity J), which is an antihypertensive agent. A thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.

References : Afrin S. et al.: J. Agric Food Chem., 64(11), 2263-2268, 2016; Esmaeili S. et al.: Chem Biol Interact., 265, 24-35, 2017; Li N. et al.: Bioorg Med Chem Lett., 24(1), 386-389, 2014; Tzakos A. G. et al.: Bioorg Med Chem Lett, 16(19), 5084-7, 2006; Song J. C. et al.: Clin Pharmacokinet., 41(3), 207-24, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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