Captopril methyl ester

SI-5780

Captopril methyl ester, >98% (HPLC)

CAS No. : [176036-41-2]

MDL No. : MFCD27578264

IUPAC Name : Methyl ((S)-3-mercapto-2-methylpropanoyl)-L-prolinate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	325.00		Back Order	Estimated to ship on 20 September 2026
5G	1325.00		Back Order	Estimated to ship on 20 September 2026

Applications : Captopril methyl ester is an analog of Captopril, which is an antihypertensive agent. A thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC₅₀=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC₅₀ of 7.9 μM.

References : Afrin S. et al.: J. Agric Food Chem., 64(11), 2263-2268, 2016; Esmaeili S. et al.: Chem Biol Interact., 265, 24-35, 2017; Li N. et al.: Bioorg Med Chem Lett., 24(1), 386-389, 2014; Tzakos A. G. et al.: Bioorg Med Chem Lett, 16(19), 5084-7,2006; Song J. C. et al.: Clin Pharmacokinet., 41(3), 207-24,2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.