CB2 agonist

SI-7279

CB2 agonist, >98% (HPLC)

IUPAC Name : 4-(3-(4-Fluoro-1H-indazol-7-yl)-1,2,4-oxadiazol-5-yl)-1-(4-fluorophenyl)azepan-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a highly selective CB2 agonist from a new class of 4‑(1,2,4‑oxadiazol‑5‑yl)azepan‑2‑one derivatives. It shows strong CB2 potency (EC₅₀ = 21.0 nM, Emax = 87%) with excellent selectivity over CB1 (CB1 EC₅₀ > 30 μM; CB1/CB2 > 1428). The compound exhibits favorable pharmacokinetics and delivers significant analgesic efficacy in a rodent inflammatory‑pain model. These properties position this compound as a promising lead CB2 agonist for treating inflammatory pain and warrant further in‑depth development.

References : Non J. et al.: J. Med. Chem., 66(5), 3460-3483, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.