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CC-401

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SI-6997

CC-401, >98% (HPLC)

CAS No. : [395104-30-0]

IUPAC Name : 3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole

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Chemical Properites
Mol. Formula :
C22H24N6O
Mol. Weight :
388.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CC‑401 functions as a potent inhibitor of the JNK family, displaying Ki values of 25–50 nM across JNK1, JNK2, and JNK3. It is widely used to investigate JNK‑mediated stress‑response, inflammatory, and apoptotic signaling.

References : Ma F. Y. et al.: J. Am. Soc. Nephrol., 18(2), 472-84, 2007; Vasilevskaya I. A. et al.: Clin. Cancer Res., 21(18), 4143-52, 2015; Ma F. Y. et al.: Lab. Invest., 89(4), 470-84, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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