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CC-401 dihydrochloride

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SI-6999

CC-401 dihydrochloride, >98% (HPLC)

CAS No. : [2319601-04-0]

IUPAC Name : 3-(3-(2-(Piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride

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Chemical Properites
Mol. Formula :
C22H24N6O • 2HCl
Mol. Weight :
461.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CC‑401 dihydrochloride functions as a potent inhibitor of the JNK family, displaying Ki values of 25–50 nM across JNK1, JNK2, and JNK3. It is widely used to investigate JNK‑mediated pathways involved in inflammation, apoptosis, and cellular stress responses.

References : Vasilevskaya I. A. et al.: Clin. Cancer Res., 21(18), 4143-52, 2015; Ma F. Y. et al.: Lab Invest., 89(4), 470-84, 2009; Ma F. Y. et al.: J. Am Soc. Nephrol., 18(2), 472-84, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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