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CC-90001

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SI-6882

CC-90001, >98% (HPLC)

CAS No. : [1403859-14-2]

IUPAC Name : 2-(tert-Butylamino)-4-(((1R,3R,4R)-3-hydroxy-4-methylcyclohexyl)amino)pyrimidine-5-carboxamide

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Chemical Properites
Mol. Formula :
C16H27N5O2
Mol. Weight :
321.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CC‑90001 selectively inhibits JNK signaling, exhibiting strong oral activity and a 12.9‑fold preference for JNK1 over JNK2 in cell‑based assays. It is a valuable tool compound for investigating JNK‑mediated mechanisms in idiopathic pulmonary fibrosis.

References : Bennett B. et al.: American Journal of Respiratory and Critical Care Medicine, 195, A5409, 2017; Kolb M. et. al.: Respir Med., 131, 49-57, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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