CC-90005

SI-6745

CC-90005, >98% (HPLC)

CAS No. : [1799574-70-1]

IUPAC Name : 2-(((4-(2,2-Difluoropropoxy)pyrimidin-5-yl)methyl)amino)-4-(((1R,4S)-4-hydroxy-3,3-dimethylcyclohexyl)amino)pyrimidine-5-carbonitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CC‑90005 selectively targets PKC‑θ with nanomolar potency (IC₅₀ = 8 nM) and shows markedly reduced activity toward PKC‑δ. By inhibiting IL‑2 expression, it attenuates T‑cell activation, making it a valuable tool for dissecting PKC‑θ–mediated immune responses.

References : Papa P. et al.: J. Med. Chem., 64(16), 11886-11903, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.