CCG-258208

SI-7890

CCG-258208, >98% (HPLC)

CAS No. : [2055990-90-2]

Synonyms : GRKs-IN-1

IUPAC Name : N-((1H-Pyrazol-3-yl)methyl)-5-((3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)piperidin-4-yl)-2-fluorobenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CCG-258208 inhibits GRK2 with low‑nanomolar potency (IC₅₀= 30 nM) and shows high selectivity relative to GRK5 (230‑fold) and GRK1/PKA/ROCK1 (>2500‑fold). Its pharmacological profile supports its use in probing GRK2‑driven mechanisms relevant to heart‑failure pathophysiology.

References : Waldschmidt H. V. et al.: J. Med. Chem., 60(7), 3052-3069, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.