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CCT-374705

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SI-7889

CCT-374705, >98% (HPLC)

CAS No. : [2640647-90-9]

IUPAC Name : (S)-10-((3-Chloro-2-fluoropyridin-4-yl)amino)-2-cyclopropyl-3,3-difluoro-7-methyl-1,2,3,4-tetrahydro-[1,4]oxazepino[2,3-c]quinolin-6(7H)-one

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H18ClF3N4O2
Mol. Weight :
450.85
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CCT-374705 inhibits BCL6 with low‑nanomolar potency (IC50 = 4.8 nM) and suppresses cancer‑cell proliferation in vitro. It also demonstrates strong antitumor efficacy in lymphoma xenograft models, making it valuable for exploring BCL6‑dependent oncogenic pathways.

References : Harnden A. C. et al.: J. Med. Chem., 66(8), 5892-5906, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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