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CE-224535

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SI-6522

CE-224535, >98% (HPLC)

CAS No. : [724424-43-5]

IUPAC Name : (R)-2-Chloro-5-(4-(2-hydroxy-3-methoxypropyl)-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)-N-((1-hydroxycycloheptyl)methyl)benzamide

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Chemical Properites
Mol. Formula :
C22H29ClN4O6
Mol. Weight :
480.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CE‑224535 selectively inhibits the P2X7 receptor, making it a useful tool compound for investigating P2X7‑dependent pathways involved in inflammation, cytokine release, and immune regulation.

References : Stock T. C. et al.: J Rheumatol, 39(4), 720-7, 2012; Duplantier A. J. et al.: Bioorg Med. Chem. Lett., 21(12), 3708-11, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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