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Cefepime sulfoxide

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Cefepime sulfoxide, >98%

CAS No. : [112258-91-0]

IUPAC Name : (E)-7-(2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 5-oxide

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Chemical Properites
Mol. Formula :
C19H24N6O6S2
Mol. Weight :
496.56
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Cefepime, which is a broad-spectrum cephalosporin that can cross the blood-brain barrier. Cefepime is effective against both Gram-positive and Gram-negative aerobic bacteria. However, Cefepime may cause neurotoxicity.

References : Yahav D. et al.: Lancet Infect Dis., 7(5), 338-48, 2007; Barradell L. B. et al.: Drugs 47(3), 471-505, 1994; Payne L. E. et al.: Crit Care 21(1), 276, 2017; Mathe A. et al.: Lab Anim., 40(3), 296-300, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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