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Celecoxib carboxylic acid

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SL-4701

Celecoxib carboxylic acid, >98%

CAS No. : [170571-01-4]

IUPAC Name : 4-(1-(4-Sulfamoylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzoic acid

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Chemical Properites
Mol. Formula :
C17H12F3N3O4S
Mol. Weight :
411.36
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Celecoxib, which is a COX-2 selective nonsteroidal anti-inflammatory drug. It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

References : Penning T. D. et al.: J. Med. Chem., 40(9), 1347-1365, 1997; Liu D. B. et al.: Acta Pharmacol Sin., 33(5), 682-690, 2012; Hunter N. R. et al.: Int J. Radiat Oncol Biol Phys., 85(2), 472-476, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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