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Cenicriviroc

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SI-6111

Cenicriviroc, >98% (HPLC)

CAS No. : [497223-25-3]

Synonyms : TAK-652; TBR-652

IUPAC Name : (S,E)-8-(4-(2-Butoxyethoxy)phenyl)-1-isobutyl-N-(4-(((1-propyl-1H-imidazol-5-yl)methyl)sulfinyl)phenyl)-1,2,3,4-tetrahydrobenzo[b]azocine-5-carboxamide

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Chemical Properites
Mol. Formula :
C41H52N4O4S
Mol. Weight :
696.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Cenicriviroc functions as an orally active CCR2/CCR5 antagonist with additional inhibitory activity against HIV‑1 and HIV‑2. It exerts broad anti‑inflammatory and anti‑infective effects, making it a valuable tool for investigating chemokine‑receptor pathways and immune dysregulation.

References : Lefebvre E. et al.: PLoS One, 11(6), e0158156, 2016; Kuwata T. et al.: Antimicrob. Agents Chemother., 60(1), 437-5, 2015; Visseaux B. et al.: PLoS One, 10(8), e0134904, 2015; Lalezari J. et al.: J. Acquir. Immune. Defic. Syndr., 57(2), 118-25, 2011; Baba M. et al.: Antimicrob. Agents Chemother, 49(11), 4584-91, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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