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SI-4894

Cenisertib, >98% (HPLC)

CAS No. : [871357-89-0]

MDL No. : MFCD22124463

Synonyms : AS-703569; AS703569; R763

IUPAC Name : (1R,2R,3S,4S)-3-((5-Fluoro-2-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide

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Chemical Properites
Mol. Formula :
C24H30FN7O
Mol. Weight :
451.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AS-703569 is a potent inhibitor of aurora kinases and exhibited significant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo. Inhibition of aurora kinases has the potential to be a new addition to the treatment of cancers.

References : Mc Laughlin J. et al.: J. Cancer Res Clin Oncol.,136(1), 99-113, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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