Centrinone-B

SI-8077

Centrinone-B, >98% (HPLC)

CAS No. : [1798871-31-4]

Synonyms : LCR-323

IUPAC Name : 2-((2-Fluoro-4-((2-fluoro-3-nitrobenzyl)sulfonyl)phenyl)thio)-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(piperidin-1-yl)pyrimidin-4-amine

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Centrinone‑B is a potent PLK4 inhibitor with exceptional selectivity and a K_i of 0.59 nM. Its high affinity for PLK4 enables precise interrogation of centrosome duplication and PLK4‑driven cellular processes.

References : Wong Y. L. et al.: Science, 348(6239), 1155-60, 2015; Denu R. A. et al.: Mol. Cancer Res., 16(3), 517-527, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.