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CAS No. : [1352226-88-0]
Synonyms : AZD-6738
IUPAC Name : (R)-Imino(methyl)(1-(6-((R)-3-methylmorpholino)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)cyclopropyl)-l6-sulfanone
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H24N6O2S | Mol. Weight : 412.51 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Ceralasertib selectively inhibits ATR with nanomolar potency (IC50 = 1 nM) and shows good oral exposure. It is a valuable tool compound for probing ATR‑dependent DNA repair pathways and evaluating therapeutic strategies targeting replication stress in cancer.
References : Vendetti F.P. et al.: Oncotarget, 6(42), 44289-305, 2015; Kwok M. et al.: Blood, 127(5), 582-95, 2016; Min A. et al.: Mol. Cancer Ther., 16(4),566-577, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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