Cerdulatinib

SI-6282

Cerdulatinib, >98% (HPLC)

CAS No. : [1198300-79-6]

Synonyms : PRT-062070; PRT-2070

IUPAC Name : 4-(Cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Cerdulatinib selectively inhibits TYK2 with sub‑nanomolar potency (IC₅₀ = 0.5 nM) and additionally targets JAK1/2/3 and SYK with low‑nanomolar IC₅₀ values. Its combined JAK/SYK blockade makes it a valuable tool for dissecting complex immune‑regulatory signaling networks.

References : Guo A. et al.: Oncotarget., 8(8), 12953-12967, 2017; Coffey G. et al.: J. Pharmacol. Exp. Ther., 351(3), 538-48, 2014; Ma J. et al.: Oncotarget., 6(41), 43881-96, 2015; Blunt M. D. et al.: Clin. Cancer Res., 23(9), 2313-2324, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.