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CAS No. : [1369761-01-2]
Synonyms : PRT-062070 hydrochloride; PRT-2070 hydrochloride
IUPAC Name : 4-(Cyclopropylamino)-2-((4-(4-(ethylsulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H27N7O3S • HCl | Mol. Weight : 482 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Cerdulatinib hydrochloride selectively inhibits SYK and JAK kinases with low‑nanomolar potency (IC50 = 32 nM for SYK; 0.5/12/6/8 nM for TYK2/JAK1/JAK2/JAK3). As an orally active, reversible ATP‑competitive inhibitor, it is valuable for dissecting signaling pathways involved in autoimmune disease and B‑cell–driven cancers.
References : Coffey G. et al., J. Pharmacol. Exp. Ther., 351(3), 538-48, 2014. Ishikawa C. et al.: Int. J. Oncol., 53(4), 1681-1690, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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