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Ceritinib

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SI-3488

Ceritinib, >98% (HPLC)

CAS No. : [1032900-25-6]

MDL No. : MFCD26142648

Synonyms : LDK378

IUPAC Name : 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G45.00
Back Order  Estimated to ship on 04 October 2026
5G175.00
Back Order  Estimated to ship on 04 October 2026
10G335.00
Back Order  Estimated to ship on 04 October 2026
25G695.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C28H36ClN5O3S
Mol. Weight :
558.14
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ceritinib is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.

References : Flick C. A et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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