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Cetirizine-d8 N-oxide

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SL-6350

Cetirizine-d8 N-oxide, >98%

CAS No. : [1216444-13-1]

IUPAC Name : 1-(2-(Carboxymethoxy)ethyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine-d8 1-oxide

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Chemical Properites
Mol. Formula :
C21H17D8ClN2O4
Mol. Weight :
412.94
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version metabolite of Cetirizine, which is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. Cetirizine is a specific, orally active and long-acting histamine H1-receptor antagonist.

References : Caroline M. S. et al.: Drugs 46(6), 1055•1080, 1993; Shih M. Y. et al.: Allergy Asthma Proc., 29(5), 480-5, 2008; Shimizu T. et al.: Clin Exp Allergy 34(1), 103-9, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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