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Cetirizine N-(2-ethoxyacetate)

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SL-6355

Cetirizine N-(2-ethoxyacetate), >98%

Synonyms : 2-(p-Chlorobenzhydrylpiperazine)-[N,N-bis(2-ethoxyacetic acid)]

IUPAC Name : 2-(2-(1-(2-(Carboxymethoxy)ethyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-ium-1-yl)ethoxy)acetate

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Chemical Properites
Mol. Formula :
C25H31ClN2O6
Mol. Weight :
490.98
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Cetirizine, which is a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. Cetirizine is a specific, orally active and long-acting histamine H1-receptor antagonist.

References : Caroline M. S. et al.: Drugs 46(6), 1055-1080, 1993; Shih M. Y. et al.: Allergy Asthma Proc., 29(5), 480-5, 2008; Shimizu T. et al.: Clin Exp Allergy 34(1), 103-9, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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