CH-7233163

SI-7971

CH-7233163, >98% (HPLC)

CAS No. : [2923365-71-1]

IUPAC Name : N-(2-(1-(Cyclopropylsulfonyl)-1H-pyrazol-4-yl)pyrimidin-4-yl)-5-isopropyl-7-(4-methylpiperazin-1-yl)-9-(2,2,2-trifluoroethoxy)-5H-pyrido[4,3-b]indol-3-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CH-7233163 selectively inhibits the EGFR Del19/T790M/C797S triple mutant through noncovalent, ATP‑competitive binding. It overcomes Osimertinib resistance, blocks EGFR phosphorylation in engineered NIH3T3 cells, and shows antitumor effects in models of EGFR‑driven disease.

References : Kashima K. et al.: Mol. Cancer Ther., 19(11), 2288-2297, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.