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Chidamide

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SL-1619

Chidamide, >98%

CAS No. : [743420-02-2]

MDL No. : MFCD18382123

Synonyms : HBI-8000; CS055

IUPAC Name : (E)-N-(2-Amino-5-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide

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Chemical Properites
Mol. Formula :
C22H19FN4O2
Mol. Weight :
390.41
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Chidamide is a synthetic benzamide-type HDACi which mainly acts as a class I HDACi (inhibiting HDAC1, HDAC2, HDAC3 and HDAC8 with IC50 of 95, 160, 67 and 733 nM, respectively).

References : Ning Z. Q. et al. Cancer Chemother Pharmacol., 69(4), 901-909, 2012; Gong K. et al.: Biochem., J. 443(3), 735-746, 2012; Zhao B. et al. Oncol Rep., 33(1), 304-310, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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