Cholesterol impurity 1

SL-9337

Cholesterol impurity 1, >98%

CAS No. : [1958016-09-5]

IUPAC Name : (S)-2-((3S,8S,9S,10R,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-methoxy-N-methylpropanamide

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Applications : This is an impurity of Cholesterol, which is the primary sterol found in mammals, comprising 20-25% of the structural components of the plasma membrane. Plasma membranes allow water to pass through easily but are comparatively resistant to ions and protons. Cholesterol influences the fluidity and permeability properties of the membrane and affects the functions of transporters and signaling proteins. Additionally, cholesterol acts as an endogenous agonist for estrogen-related receptor α (ERRα).

References : Casaburi I. et al.: Front Endocrinol (Lausanne) 9, 525, 2018; Dietschy J. M. et al.: J. Lipid Res., 45(8), 1375-97, 2004; Puskás L. G. et al.: FEBS Lett., 562(1-3), 99-104, 2004; Onody A. et al.: Cardiovasc Res., 58(3), 663-70, 2003; Baumer Y. et al.: Nat Commun., 8(1), 1129, 2017; Finking G. et al.: Atherosclerosis. 135(1), 1-7, 1997; Fan J. et al.: Methods Mol Biol., 2419, 413-431, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.