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CHS-828 nicotinate

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SI-7220

CHS-828 nicotinate, >98% (HPLC)

CAS No. : [1160589-73-0]

Synonyms : GMX-1778 nicotinate

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H22ClN5O • C6H5NO2
Mol. Weight :
494.98
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CHS‑828 nicotinate is a competitive NAMPT inhibitor with an IC50 below 25 nM. It depletes intracellular NAD⁺ levels, producing cytotoxic effects and exhibiting potent anticancer activity.

References : Watson M. et al.: Mol. Cell. Biol., 29(21), 5872-88, 2009; Cerna D. et al.: J. Biol. Chem., 287(26), 22408-17, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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