CI-1040

SI-5528

CI-1040, >98% (HPLC)

CAS No. : [212631-79-3]

MDL No. : MFCD02683961

Synonyms : PD184352

IUPAC Name : 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
5G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CI-1040 is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1. CI-1040 is developing for potential treatment of breast cancer and other cancers.

References : Allen L. F. et al.: Semin Oncol., 30(5 Suppl 16), 105-16, 2003; Wei C. R. et al.: Eur Rev Med Pharmacol Sci., 20(10), 1961-8, 2016; Kramer B. W. et al.: BMC Cancer, 4, 24,2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.