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CID-2745687

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SI-7675

CID-2745687, >98% (HPLC)

CAS No. : [264233-05-8]

IUPAC Name : Methyl (E)-5-((2-(tert-butylcarbamothioyl)hydrazineylidene)methyl)-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate

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Chemical Properites
Mol. Formula :
C17H19F2N5O2S
Mol. Weight :
395.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CID-2745687 selectively antagonizes GPR35 through reversible and competitive binding, displaying strong affinity (Ki = 12.8 nM). It is widely used to dissect GPR35‑dependent cellular responses and downstream signaling mechanisms.

References : Zhao P. et al.: Mol .Pharmacol., 78(4), 560-8, 2010; Jenkins L. et al.: J. Pharmacol. Exp. Ther., 343(3), 683-95, 2012; Mi-Jeong Kim et al.: Biomol. Ther (Seoul), 28(1), 92-97, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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