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Ciforadenant

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SI-7000

Ciforadenant, >98% (HPLC)

CAS No. : [1202402-40-1]

Synonyms : V-81444; CPI-444

IUPAC Name : (S)-7-(5-Methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

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Chemical Properites
Mol. Formula :
C20H21N7O3
Mol. Weight :
407.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ciforadenant functions as a potent and selective A2A receptor antagonist with strong oral activity. Through inhibition of adenosine‑driven immune suppression, it reactivates antitumor immune pathways and demonstrates clear antitumor efficacy.

References : Stephen W. et al.: Cancer Immunol. Res., 4(11), PR04, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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