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Cilastatin EP impurity B

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SL-2903

Cilastatin EP impurity B, >96%

IUPAC Name : (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic acid

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Chemical Properites
Mol. Formula :
C21H34N2O6S
Mol. Weight :
442.57
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Cilastatin (Cilastatin EP impurity B), which is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor, an antibacterial adjunct.

References : Keynan S. et al.: Antimicrob Agents Chemother., 39(7),1629-1633, 1995; Koller M. et al.: Biochem Biophys Res Commun., 131(2), 974-979, 1985.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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