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Cilofexor tromethamine

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SI-6090

Cilofexor tromethamine, >98% (HPLC)

CAS No. : [2253764-93-9]

Synonyms : GS-9674 tromethamine

IUPAC Name : 2-Amino-2-(hydroxymethyl)propane-1,3-diol 2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinate

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C28H22Cl3N3O5 • C4H11NO3
Mol. Weight :
707.99
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Cilofexor tromethamine activates FXR and improves cholestasis‑related and liver‑injury biomarkers. It is well tolerated in patients without cirrhosis and produces significant improvements in liver biochemical and cholestatic parameters, supporting its potential utility in PSC management.

References : Trauner M. et al.: Hepatology, 70(3), 788-801, 2019; Patel K. et al.: Hepatology, 2020; Schwab P. et al.: 68, 1, S471-S472, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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