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Cinacalcet (R,R)-diastereomer 2 hydrochloride salt

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Cinacalcet (R,R)-diastereomer 2 hydrochloride salt, >98%

Related CAS No. : [2059891-97-1] of the free base compound

IUPAC Name : (R)-N-((R)-1-(Naphthalen-1-yl)ethyl)-2-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

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Chemical Properites
Mol. Formula :
C22H22F3N . HCl
Mol. Weight :
393.88
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Cinacalcet, which is a calcimimetic medication that enhances the sensitivity of calcium-sensing receptors (CaSR) on parathyroid cells to extracellular calcium; Cinacalcet is used to manage chronic kidney disease in patients undergoing dialysis and to treat elevated blood calcium levels resulting from parathyroid gland disorders.

References : Colloton M. et al.: Kidney Int., 67(2), 467-76, 2005; Bushinsky D. A. et al.: Kidney Int., 69(9), 1586-92, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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