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Cinaciguat hydrochloride

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SI-6530

Cinaciguat hydrochloride, >98% (HPLC)

CAS No. : [646995-35-9]

Synonyms : BAY-582667 hydrochloride

IUPAC Name : 4-(((4-Carboxybutyl)(2-((4-phenethylbenzyl)oxy)phenethyl)amino)methyl)benzoic acid hydrochloride

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Chemical Properites
Mol. Formula :
C36H39NO5 • HCl
Mol. Weight :
602.17
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Cinaciguat hydrochloride activates sGC with low‑nanomolar potency (EC50 = 15 nM in platelets), promoting cGMP generation through an NO‑independent mechanism. Its pharmacological profile supports applications in vascular biology and cardiopulmonary research.

References : Roy B. et al.: Br. J. Pharmacol., 153(7), 1495-504, 2008; Thoonen R. et al.: Nat. Commun., 6, 8482, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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