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CJ-15208

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SI-7631

CJ-15208, >98% (HPLC)

CAS No. : [210236-47-8]

IUPAC Name : (3S,6S,9S,14aS)-6-((1H-indol-3-yl)methyl)-3,9-dibenzyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone

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Chemical Properites
Mol. Formula :
C34H35N5O4
Mol. Weight :
577.68
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CJ‑15208 functions as a potent κ‑opioid receptor antagonist with significant analgesic efficacy in mice. Its stereoisomers show receptor‑subtype‑specific activity, with distinct κ‑ and δ‑receptor antagonistic profiles. Importantly, none of the stereoisomers impair respiration or promote tolerance, underscoring their potential utility in designing safer opioid‑based pain therapeutics.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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