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CK-636

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SL-321

CK-636, 97%

CAS No. : [442632-72-6]

MDL No. : MFCD03036245

IUPAC Name : N-​[2-​(2-​Methyl-​1H-​indol-​3-​yl)​ethyl]​-​2-​thiophenecarboxamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
10MG35.00
Back Order  Estimated to ship on 04 October 2026
25MG75.00
Back Order  Estimated to ship on 04 October 2026
50MG125.00
Back Order  Estimated to ship on 04 October 2026
100MG175.00
Back Order  Estimated to ship on 04 October 2026
250MG295.00
Back Order  Estimated to ship on 04 October 2026
500MG455.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C16H16N2OS
Mol. Weight :
284.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation. CK-636 inserts into the hydrophobic core of Arp3 and alters its conformation. Both classes of compounds inhibit formation of actin filament comet tails by listeria and podosomes by monocytes.

References : Nolen B.J. et. al.: Nature, 460 (7258), 1031, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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