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Clevidipine

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Clevidipine, >98%

CAS No. : [167221-71-8]

IUPAC Name : 3-((Butyryloxy)methyl) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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1GRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C21H23Cl2NO6
Mol. Weight :
456.32
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Clevidipine is a selective, short-acting L-type calcium channel blocker (IC50: 7.1 nM) that causes rapid vasodilation by inhibiting extracellular calcium influx, lowering peripheral vascular resistance, and effectively controlling acute severe hypertension. It also helps protect the myocardium from reperfusion injury by increasing nitric oxide release. Clevidipine is useful for studying acute hypertension, perioperative blood pressure control, and myocardial ischemia-reperfusion injury.

References : Pollack C. V. et al.: Ann Emerg Med., 53(3), 329-38, 2009; Gourine A. et al.: Cardiovasc Res., 51(1), 100-7, 2001; Wang Y. et al.: Biomed Chromatogr., 32(2), 2018; Wisniowska B. et al.: J. Appl Toxicol., 32(10), 858-66, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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