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Colchicine EP impurity B

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SL-6521

Colchicine EP impurity B, >98%

CAS No. : [64-86-8]

IUPAC Name : N-((7S)-1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

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Chemical Properites
Mol. Formula :
C22H25NO6
Mol. Weight :
399.44
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a conformational isomer of Colchicine and an impurity (Colchicine EP impurity B), which is a microtubule polymerization inhibitor, used to treat gout and behcet's disease.

References : Bonfoco E. et al.: Exp Cell Res., 218(1), 189-200,1995; Hastie S. B. Pharmacol Ther., 51(3), 377-401,1991; Otani K. et al.: Sci Rep., 6, 32587, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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