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Colchicine EP impurity D

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SL-6523

Colchicine EP impurity D, >98%

CAS No. : [477-29-2]

MDL No. : MFCD27967295

Synonyms : N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; 3-Demethylcolchicine glucoside; Colchicoside

IUPAC Name : N-((S)-1,2,10-Trimethoxy-9-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

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Chemical Properites
Mol. Formula :
C27H33NO11
Mol. Weight :
547.56
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Colchicine (Colchicine EP impurity D), which is a microtubule polymerization inhibitor, used to treat gout and behcet's disease.

References : Bonfoco E. et al.: Exp Cell Res., 218(1), 189-200,1995; Hastie S. B. Pharmacol Ther., 51(3), 377-401,1991; Otani K. et al.: Sci Rep., 6, 32587, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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