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Combretastatin A4

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SL-097

Combretastatin A4, 98%

CAS No. : [117048-59-6]

MDL No. : MFCD03453309

Synonyms : CRC 87-09; NSC 817373; CA4

IUPAC Name : 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
10MG20.00
Back Order  Estimated to ship on 20 September 2026
25MG34.00
Back Order  Estimated to ship on 20 September 2026
50MG65.00
Back Order  Estimated to ship on 20 September 2026
100MG85.00
Back Order  Estimated to ship on 20 September 2026
250MG155.00
Back Order  Estimated to ship on 20 September 2026
500MG255.00
Back Order  Estimated to ship on 20 September 2026
1G425.00
Back Order  Estimated to ship on 20 September 2026
5G1425.00
Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C18H20O5
Mol. Weight :
316.35
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Combrestatin A4 (CA4) is a potent inhibitor of tubulin polymerization and displays strong inhibitory activity on tumor cell growth and shown to inhibit tumor growth in several cell lines including IMR32 (neuroblastoma), Hs746T (gastric carcinoma), CFPAC-1 (pancreatic carcinoma), and MCF-7 (breast cancer) with IC50 values of 2.16, 5.20, 3.46, and 18.47 nM, respectively.

References : Pettit.G. R. et. al.: J. Med. Chem., 38, 1666, 1995.

Storage : Desiccate at -20°C

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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