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Conivaptan hydrochloride

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SI-7482

Conivaptan hydrochloride, >98% (HPLC)

CAS No. : [168626-94-6]

Synonyms : YM-087

IUPAC Name : N-(4-(2-Methyl-3,4,5,6-tetrahydrobenzo[b]imidazo[4,5-d]azepine-6-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C32H26N4O2 • HCl
Mol. Weight :
535.04
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Conivaptan hydrochloride selectively antagonizes vasopressin V1A and V2 receptors with Ki values of 0.48 nM and 3.04 nM, respectively. Its dual‑receptor profile makes it a valuable tool for probing vasopressin‑mediated pathways in renal and cardiovascular systems.

References : Tahara A. et al.: J. Pharmacol. Exp. Ther., 282(1), 301-8, 1997; Tahara A. et al. Cardiovasc Res., 38(1), 198-205, 1998; Nakayama S, et al. Neurocrit Care., 24(2), 273-82, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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