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CP-465022 hydrochloride

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SI-7237

CP-465022 hydrochloride, >98% (HPLC)

CAS No. : [1785666-59-2]

IUPAC Name : (E)-3-(2-Chlorophenyl)-2-(2-(6-((diethylamino)methyl)pyridin-2-yl)vinyl)-6-fluoroquinazolin-4(3H)-one hydrochloride

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Chemical Properites
Mol. Formula :
C26H24ClFN4O • HCl
Mol. Weight :
499.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CP‑465022 hydrochloride is a potent, selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. It inhibits kainate‑induced responses in rat cortical neurons with an IC50 of 25 nM and serves as a tool for investigating AMPA receptor function in physiological and pathological contexts.

References : Lazzaro T. J. et al.: Neuropharmacology, 42(2), 143-53, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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