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SL-1356
Crizotinib, >98%
CAS No. : [877399-52-5]
MDL No. : MFCD12407409
Synonyms : (R)-Crizotinib; PF 02341066; PF 2341066
IUPAC Name : 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 1G | 50.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 5G | 165.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 10G | 265.00 | In Stock | Estimated to ship on 20 September 2026 | |
| 25G | 495.00 | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H22Cl2FN5O | Mol. Weight : 450.34 |
Appearance : Beige solid | Melting Point : 201-203oC (lit.) |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley. This is an anti-cancer drug, used for the treatment of non-small cell lung carcinoma (NSCLC).
References : Tucker E. R. et al.: Mol. Oncol., 11(8), 996, 2017; Liu H. et al.: Cancer Discov., 8(3), 354, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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