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CY-9d

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SI-6449

CY-9d, >98% (HPLC)

CAS No. : [2071682-80-7]

IUPAC Name : 1-(5-(Tert-butyl)isoxazol-3-yl)-3-(2-methyl-4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea

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Chemical Properites
Mol. Formula :
C20H24N6O3
Mol. Weight :
396.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CY‑9d is a potent MEK/ERK pathway inhibitor, suppressing MEK‑driven ERK phosphorylation and downstream MAPK signaling. In cancer models—including triple‑negative breast cancer (TNBC)—Cy‑9d shows strong anti‑proliferative and pro‑apoptotic activity, making it a useful tool compound for studying MAPK‑dependent tumor biology and evaluating MEK/ERK‑targeted therapeutic strategies.

References : Liao M. et al.: J. Med. Chem., 64(5), 2382-2418, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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