Cyclo (L-leucyl-L-prolyl)peptide (CLP)

SI-6251

Cyclo (L-leucyl-L-prolyl)peptide (CLP), >98% (HPLC)

IUPAC Name : (3S,8aS)-3-Isopentyl-8a-methylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a pyrrolo‑pyrazinedione scaffold identified as a novel EGFR inhibitor with activity in triple‑negative breast cancer (TNBC). This compact bicyclic chemotype suppresses EGFR‑driven signaling in EGFR‑dependent TNBC models, offering a non‑classical, low‑molecular‑weight EGFR inhibitory scaffold for TNBC research.

References : Liao M. et al.: J. Med. Chem., 64(5), 2382-2418, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.