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CZ-415

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SI-6330

CZ-415, >98% (HPLC)

CAS No. : [1429639-50-8]

IUPAC Name : (S)-1-(4-(7,7-Dimethyl-4-(3-methylmorpholino)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea

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Chemical Properites
Mol. Formula :
C22H29N5O4S
Mol. Weight :
459.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : CZ-415 is a strong and selective mTOR inhibitor (pIC50 = 8.07) that blocks signaling through both mTORC1 and mTORC2. Its dual‑complex inhibition makes it valuable for probing mTOR‑dependent cellular growth and survival mechanisms.

References : Cansfield A. D. et al.: ACS. Med. Chem. Lett., 7(8), 768-73, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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