CZC-54252 hydrochloride

SI-8021

CZC-54252 hydrochloride, >98% (HPLC)

CAS No. : [1784253-05-9]

IUPAC Name : N-(2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CZC‑54252 hydrochloride selectively inhibits LRRK2 with low‑nanomolar potency against both WT and G2019S variants. It effectively reduces G2019S‑LRRK2‑driven neuronal injury (EC₅₀ ≈ 1 nM) and displays clear neuroprotective activity, supporting its use in studies of LRRK2‑mediated neurodegeneration.

References : Ramsden N. et al.: ACS. Chem. Biol., 6(10), 1021-8, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.